Genes and Conditions Controlling Mammalian Pre- and Post-implantation Embryo Development
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منابع مشابه
Genes and Conditions Controlling Mammalian Pre- and Post-implantation Embryo Development
Embryo quality during the in vitro developmental period is of great clinical importance. Experimental genetic studies during this period have demonstrated the association between specific gene expression profiles and the production of healthy blastocysts. Although the quality of the oocyte may play a major role in embryo development, it has been well established that the post - fertilization pe...
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Understanding human pre-implantation development has important implications for assisted reproductive technology (ART) and for human embryonic stem cell (hESC)-based therapies. Owing to limited resources, the cellular and molecular mechanisms governing this early stage of human development are poorly understood. Nonetheless, recent advances in non-invasive imaging techniques and molecular and g...
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Introduction: Women with poorly controlled insulin-dependent diabetes mellitus (IDDM) have a much higher incidence of early pregnancy complications, these include spontaneous miscarriages, early growth delay, and congenital malformations. Most of the investigations have been devoted to the early post implantation and organogenesis period of pregnancy. In this research we studied the hyperglycem...
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Background: Hyaluronan (HA) is a structural component of extracellular matrix synthesised by HA synthases HAS1-3, which produce HA of different molecular sizes with distinct biological functions associated with reproductive processes. Hyaluronidase (HYAL) cleaves the HA into biologically active small fragments which are known to regulate cell proliferation through CD44 receptor signaling. HA is...
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Clinical studies have shown that in pathological conditions such as endometriosis and reproductive tract infection (male and female) there is an activation status of macrophages that produce large quantities of nitric oxide (NO) in addition to other effector molecules. Large amounts of NO may have embryotoxic roles and produce infertility. This study was designed to evaluate the effect of diffe...
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ژورنال
عنوان ژورنال: Current Genomics
سال: 2015
ISSN: 1389-2029
DOI: 10.2174/1389202916666141224205025